Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | DHPS | P49366 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306550 | 1.00 | DDB1 (0.48) | DDB1CRBNL3MBTL1DHPSKMT2A | |
| SCHEMBL9305095 | 0.87 | DDB1 (0.49) | DDB1CRBNL3MBTL1DHPSKMT2A | |
| SCHEMBL9305088 | 0.87 | DDB1 (0.49) | DDB1CRBNL3MBTL1DHPSKMT2A | |
| SCHEMBL4130800 | 0.82 | ACHE (0.49) | DDB1CRBNL3MBTL1DHPSKMT2A | |
| SCHEMBL4130797 | 0.82 | ACHE (0.49) | DDB1CRBNL3MBTL1DHPSKMT2A | |
| SCHEMBL20620191 | 0.76 | ALDH1A1 (0.46) | DDB1CRBNL3MBTL1DHPSKMT2A | |
| SCHEMBL8248998 | 0.74 | DDB1 (0.59) | DDB1CRBNL3MBTL1DHPSKMT2A | |
| SCHEMBL11052192 | 0.73 | KMT2A (0.59) | DDB1CRBNL3MBTL1KMT2APOLB | |
| SCHEMBL9037778 | 0.72 | DHPS (0.36) | DDB1CRBNL3MBTL1DHPSKMT2A | |
| SCHEMBL7837188 | 0.71 | DDB1 (0.56) | DDB1CRBNL3MBTL1DHPSKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360812-A | Fused 1,2,5-oxadiazole-2-oxides and their use | CASSELLA AKTIENGESELLSCHAFT (DE) | 1994-11-01 | — | — | US | disclosed |
| EP-0574726-A1 | Annelated 1,2,5-oxadiozole-2 oxides and their use as pharmacological agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-12-22 | — | — | EP | disclosed |