Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13773006 | 0.94 | THRA (0.57) | HPGDHSD17B10THRATHRBMEN1 | |
| SCHEMBL13773009 | 0.91 | THRA (0.64) | THRATHRBPDE4BTSHRSMPD1 | |
| SCHEMBL13773010 | 0.88 | SMPD1 (0.58) | THRATHRBPDE4BPDE4DSMPD1 | |
| SCHEMBL480333 | 0.87 | MAPT (0.57) | MEN1KMT2APDE4BSMN1; SMN2CYP1A2 | |
| SCHEMBL13773013 | 0.84 | THRA (0.45) | HPGDTHRATHRBMEN1KMT2A | |
| SCHEMBL4141881 | 0.84 | KDM4E (0.53) | THRATHRBMEN1KMT2AKDM4E | |
| SCHEMBL13773008 | 0.83 | MEN1 (0.47) | HPGDMEN1KMT2APDE4BSMN1; SMN2 | |
| SCHEMBL13773002 | 0.82 | THRA (0.43) | HPGDTHRATHRBMEN1KMT2A | |
| SCHEMBL4144753 | 0.82 | KMT2A (0.52) | HPGDMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL4145207 | 0.82 | KDM4E (0.70) | HPGDMEN1KMT2APDE4BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371296-A | Light stability, sunburn prevention | KAO CORPORATION (JP) | 1994-12-06 | — | — | US | claimed |
| EP-0504844-A2 | 4,4-Dimethyl-1-phenylpentane-1,3-dione derivative and UV ray absorbent and cosmetic containing the same | KAO CORPORATION (JP) | 1992-09-23 | — | — | EP | claimed |
| US-5371296-A | Light stability, sunburn prevention | KAO CORPORATION (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5191121-A | Sunscreen | KAO CORPORATION (JP) | 1993-03-02 | — | — | US | disclosed |
| EP-0504844-A2 | 4,4-Dimethyl-1-phenylpentane-1,3-dione derivative and UV ray absorbent and cosmetic containing the same | KAO CORPORATION (JP) | 1992-09-23 | — | — | EP | disclosed |