Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4141881 | 0.87 | KDM4E (0.53) | KDM4EALDH1A1MEN1KMT2APOLB | |
| SCHEMBL480333 | 0.85 | MAPT (0.57) | PDE4BALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28326914 | 0.83 | KDM4E (1.00) | KDM4EPDE4BALDH1A1MEN1KMT2A | |
| SCHEMBL4144753 | 0.82 | KMT2A (0.52) | KDM4EALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9306660 | 0.82 | HPGD (0.55) | KDM4EPDE4BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3547607 | 0.81 | KDM4E (0.72) | KDM4EPDE4BALDH1A1CYP2D6MEN1 | |
| SCHEMBL13773006 | 0.81 | THRA (0.57) | KDM4EPDE4BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14907128 | 0.80 | KDM4E (0.74) | KDM4EPDE4BALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL31737057 | 0.80 | KDM4E (0.74) | KDM4EPDE4BALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9305217 | 0.80 | KDM4E (0.74) | KDM4EPDE4BALDH1A1CYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371296-A | Light stability, sunburn prevention | KAO CORPORATION (JP) | 1994-12-06 | — | — | US | claimed |
| EP-0504844-A2 | 4,4-Dimethyl-1-phenylpentane-1,3-dione derivative and UV ray absorbent and cosmetic containing the same | KAO CORPORATION (JP) | 1992-09-23 | — | — | EP | claimed |
| US-20090169494-A1 | Sunscreen cosmetic composition | SHISEIDO COMPANY LTD (JP) | 2009-07-02 | — | — | US | disclosed |
| EP-1944012-A1 | SUNSCREEN COSMETIC COMPOSITION | Shiseido Company, Limited (JP) | 2008-07-16 | — | — | EP | disclosed |
| EP-0528380-B1 | Alkyl-aryl 1,3-propanedion silicone derivative and an external preparation for skin with the derivative compounded therein | SHISEIDO CO LTD (JP) | 1997-02-26 | — | — | EP | disclosed |
| US-5371296-A | Light stability, sunburn prevention | KAO CORPORATION (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5225583-A | Ultraviolet radiation absorbers | SHISEIDO CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| US-5191121-A | Sunscreen | KAO CORPORATION (JP) | 1993-03-02 | — | — | US | disclosed |
| EP-0528380-A1 | Alkyl-aryl 1,3-propanedion silicone derivative and an external preparation for skin with the derivative compounded therein | SHISEIDO COMPANY LIMITED (JP) | 1993-02-24 | — | — | EP | disclosed |
| EP-0504844-A2 | 4,4-Dimethyl-1-phenylpentane-1,3-dione derivative and UV ray absorbent and cosmetic containing the same | KAO CORPORATION (JP) | 1992-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090169494-A1 | Sunscreen cosmetic composition | SUN2, TYR, AHR | KDM4E 1204/4885PDE4B 4235/4885ALDH1A1 395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.