SCHEMBL480333

SCHEMBL480333

COc1ccc(C(=O)CC(=O)C(C)(C)C)cc1OC

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.57
▸ ALDH1A1 P00352 4/20 0.57
▸ MEN1 O00255 3/20 0.57
▸ KMT2A Q03164 3/20 0.57
▸ GAA P10253 2/20 0.57
▸ SMN1; SMN2 Q16637 1/20 0.57
▸ TSHR P16473 2/20 0.56
▸ CTNNB1 P35222 2/20 0.56
▸ WNT3A P56704 2/20 0.56
▸ CYP1A2 P05177 1/20 0.56
▸ CYP3A4 P08684 1/20 0.56
▸ CYP2C9 P11712 1/20 0.56
▸ CYP2C19 P33261 1/20 0.56
▸ CA12 O43570 1/20 0.54
▸ CA1 P00915 1/20 0.54
▸ CA2 P00918 1/20 0.54
▸ CA4 P22748 1/20 0.54
▸ CA6 P23280 1/20 0.54
▸ CA7 P43166 1/20 0.54
▸ TPMT P51580 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9482050 0.88 MAPT (0.51) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL9306660 0.87 HPGD (0.55) MAPTMEN1KMT2ASMN1; SMN2TSHR
SCHEMBL13773006 0.86 THRA (0.57) MAPTMEN1KMT2ASMN1; SMN2TSHR
SCHEMBL13773010 0.86 SMPD1 (0.58) PDE4BPDE4DHDAC3HDAC2
SCHEMBL4596183 0.86 MAPT (0.53) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL1659363 0.86 MAPT (0.71) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL9145097 0.86 MAPT (0.56) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL4144753 0.85 KMT2A (0.52) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL4145207 0.85 KDM4E (0.70) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL13773009 0.84 THRA (0.64) TSHRPDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 511 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2575750-A2 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE International Flora Technologies, Ltd. (US) 2013-04-10 — — EP claimed
WO-2011149929-A2 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) 2011-12-01 — — WO claimed
US-20110286946-A1 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) 2011-11-24 — — US claimed
EP-2172185-B1 Cosmetic material comprising octyl hydroxy stearate oligomer PARAHERMOSA CO LTD (JP) 2011-11-23 — — EP claimed
EP-1661583-B1 EXTERNAL PREPARATION FOR PERCUTANEOUS ADMINISTRATION CONTAINING NONSTEROIDAL ANTI-INFLAMMATORY ANALGESIC HISAMITSU PHARMACEUTICAL CO (JP) 2011-11-09 — — EP claimed
EP-1872796-B1 TRANSDERMAL PREPARATION FOR EXTERNAL USE CONTAINING NONSTEROIDAL ANTIINFLAMMATORY/ANALGESIC AGENT HISAMITSU PHARMACEUTICAL CO (JP) 2011-09-21 — — EP claimed
US-20100311700-A1 Transdermal preparation for external use containing nonsterioidal antiinflammatory/analgesic agent HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2010-12-09 — — US claimed
US-20100047185-A1 ACTVIE SUBSTANCE COMBINATION ISDIN S.A. (ES) 2010-02-25 — — US claimed
US-20080317689-A1 Transdermal Preparation for External Use Containing Antiinflammatory/Analgesic Agent HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2008-12-25 — — US claimed
EP-1872796-A1 TRANSDERMAL PREPARATION FOR EXTERNAL USE CONTAINING NONSTEROIDAL ANTIINFLAMMATORY/ANALGESIC AGENT HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2008-01-02 — — EP claimed
US-20070148216-A1 External preparation for percutaneous administration containing nonsteroidal anti-inflammatory analgesic HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2007-06-28 — — US claimed
EP-1661583-A1 EXTERNAL PREPARATION FOR PERCUTANEOUS ADMINISTRATION CONTAINING NONSTEROIDAL ANTI-INFLAMMATORY ANALGESIC HISAMITSU PHARMACEUTICAL CO. INC. (JP) 2006-05-31 — — EP claimed
US-20060073106-A1 Novel stabilized cinnamic ester sunscreen compositions DSM IP ASSETS B.V. (NL) 2006-04-06 — — US claimed
EP-1589940-A1 NOVEL STABILIZED CINNAMIC ESTER SUNSCREEN COMPOSITIONS DSM IP Assets B.V. (NL) 2005-11-02 — — EP claimed
WO-2004069216-A1 NOVEL STABILIZED CINNAMIC ESTER SUNSCREEN COMPOSITIONS DSM IP ASSETS B.V. (CH) 2004-08-19 — — WO claimed
WO-2026106274-A1 HAIR COSMETIC COMPOSITION HAVING EXCELLENT PHOTOPROTECTIVE EFFICACY 한국콜마주식회사 2026-05-21 — — WO disclosed
US-20260130832-A1 EMULSION COMPOSITION AJINOMOTO CO., INC. (JP) 2026-05-14 — — US disclosed
US-5191121-A Sunscreen KAO CORPORATION (JP) 1993-03-02 — — US disclosed
US-5146002-A Sunscreen KAO CORPORATION (JP) 1992-09-08 — — US disclosed
EP-0416564-A2 Novel aroyl ketone derivative, UV ray absorber comprising the same, and cosmetic composition containing the same KAO CORPORATION (JP) 1991-03-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260130832-A1 EMULSION COMPOSITION DGKA, DGKG, ADH1A MAPT 1370/4885ALDH1A1 60/4885MEN1 3014/4885
US-20060073106-A1 Novel stabilized cinnamic ester sunscreen compositions SUN2, NISCH, BCAS2 MAPT 439/4885ALDH1A1 259/4885MEN1 1919/4885
US-20100047185-A1 ACTVIE SUBSTANCE COMBINATION UGT2B17, TACR2, UGT1A1 MAPT 922/4885ALDH1A1 28/4885MEN1 2776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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