Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306979 | 0.88 | HPGD (0.56) | PLA2G4B | |
| SCHEMBL8085972 | 0.85 | — | — | |
| SCHEMBL9306557 | 0.83 | THRA (0.51) | THRATHRB | |
| SCHEMBL9308491 | 0.83 | THRA (0.51) | SMPD1PLA2G4BTHRATHRB | |
| SCHEMBL9306397 | 0.83 | SMPD1 (0.52) | SMPD1 | |
| SCHEMBL9306021 | 0.81 | THRA (0.52) | THRATHRB | |
| SCHEMBL9306402 | 0.81 | THRA (0.52) | THRATHRB | |
| SCHEMBL9308313 | 0.80 | CYP2D6 (0.47) | SMPD1PLA2G4B | |
| SCHEMBL9308107 | 0.80 | TRPM8 (0.55) | PLA2G4B | |
| Iodide SCHEMBL9306673 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5208247-A | Antianaphylactic agents or septic shock | AMERICAN CYANAMID COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0530444-A1 | Aryl, amide, imide, and carbamate pyridine antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |