Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9307677 | 0.85 | — | — | |
| Iodide SCHEMBL9307714 | 0.80 | THRA (0.45) | — | |
| Iodide SCHEMBL9307571 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPK1SMN1; SMN2 | |
| Iodide SCHEMBL9306678 | 0.76 | THRA (0.44) | — | |
| Iodide SCHEMBL9305550 | 0.76 | BCHE (0.43) | — | |
| Iodide SCHEMBL9307102 | 0.75 | — | — | |
| Iodide SCHEMBL9306273 | 0.75 | — | — | |
| Iodide SCHEMBL9307761 | 0.74 | THRA (0.46) | — | |
| Iodide SCHEMBL9308615 | 0.71 | THRA (0.45) | — | |
| Iodide SCHEMBL9307907 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |