SCHEMBL230980

SCHEMBL230980

c1ccc(-c2cccc3nc(-c4cc(-c5nc6cccc(-c7ccccc7)c6[nH]5)cc(-c5nc6cccc(-c7ccccc7)c6[nH]5)c4)[nH]c23)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.49
RAB9A P51151 6/20 0.49
GAA P10253 3/20 0.49
TNKS O95271 1/20 0.45
PARP1 P09874 1/20 0.45
TNKS2 Q9H2K2 1/20 0.45
HPGD P15428 7/20 0.44
ALDH1A1 P00352 6/20 0.44
SMN1; SMN2 Q16637 6/20 0.44
KDM4E B2RXH2 4/20 0.44
HSD17B10 Q99714 3/20 0.44
TP53 P04637 2/20 0.44
MAPT P10636 3/20 0.42
USP2 O75604 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
HTT P42858 2/20 0.41
GLA P06280 1/20 0.41
GFER P55789 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30872095 1.00 NPC1 (0.49) NPC1RAB9AGAATNKSPARP1
SCHEMBL27761849 0.93 NPC1 (0.56) NPC1RAB9AGAATNKSPARP1
SCHEMBL7146757 0.91 NPC1 (0.55) NPC1RAB9AGAATNKSPARP1
Water SCHEMBL28237887 0.91 NPC1 (0.55) NPC1RAB9AGAATNKSPARP1
SCHEMBL8202622 0.89 MEN1 (0.47) NPC1RAB9AGAATNKSPARP1
SCHEMBL1830193 0.85 RAB9A (0.43) NPC1RAB9AGAATNKSPARP1
SCHEMBL28136411 0.84 TNKS (0.56) NPC1RAB9AGAATNKSPARP1
SCHEMBL5842456 0.80 NPC1 (0.41) NPC1RAB9AGAATNKSPARP1
SCHEMBL11086043 0.79 ALDH1A1 (0.45) NPC1RAB9AGAAHPGDALDH1A1
SCHEMBL29178027 0.79 HTT (0.38) NPC1RAB9AGAATNKSPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12435100-B2 Perovskite solar cells PURDUE RESEARCH FOUNDATION (US) 2025-10-07 US claimed
US-12250869-B2 Mechanically robust and self-healable perovskite solar cells PURDUE RESEARCH FOUNDATION (US) 2025-03-11 US claimed
US-12116378-B2 Transition metal luminescent complexes and methods of use THE UNIVERSITY OF HONG KONG (CN) 2024-10-15 US claimed
US-20240114764-A1 MECHANICALLY ROBUST AND SELF-HEALABLE PEROVSKITE SOLAR CELLS PURDUE RESEARCH FOUNDATION (US) 2024-04-04 US claimed
US-11877504-B2 Mechanically robust and self-healable perovskite solar cells PURDUE RESEARCH FOUNDATION (US) 2024-01-16 US claimed
US-20230024217-A1 MECHANICALLY ROBUST AND SELF-HEALABLE PEROVSKITE SOLAR CELLS PURDUE RESEARCH FOUNDATION (US) 2023-01-26 US claimed
US-20220246865-A1 PEROVSKITE SOLAR CELLS PURDUE RESEARCH FOUNDATION (US) 2022-08-04 US claimed
US-20200176691-A1 TRANSITION METAL LUMINESCENT COMPLEXES AND METHODS OF USE UNIV HONG KONG (HK) 2020-06-04 US claimed
US-20200172562-A1 TRANSITION METAL LUMINESCENT COMPLEXES AND METHODS OF USE THE UNIVERSITY OF HONG KONG (HK) 2020-06-04 US claimed
EP-2318472-B1 ORGANIC LIGHT-EMITTING DIODES FROM HOMOLEPTIC SQUARE PLANAR COMPLEXES UNIV NORTH TEXAS (US) 2017-08-23 EP claimed
CN-104650862-B The preparation of the graphene quantum dot that a kind of white fluorescent is launched and application thereof 南京邮电大学 2016-08-24 CN claimed
US-20140326957-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE AND METHOD OF MANUFACTURING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-11-06 US claimed
US-8580397-B2 Organic light-emitting diodes from homoleptic square planar complexes UNIVERSITY OF NORTH TEXAS (US) 2013-11-12 US claimed
US-8518559-B2 Arylamine compounds and electronic devices AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2013-08-27 US claimed
US-20110260145-A1 ORGANIC LIGHT-EMITTING DIODES FROM HOMOLEPTIC SQUARE PLANAR COMPLEXES UNIVERSITY OF NORTH TEXAS (US) 2011-10-27 US claimed
EP-2318472-A1 ORGANIC LIGHT-EMITTING DIODES FROM HOMOLEPTIC SQUARE PLANAR COMPLEXES University Of North Texas (US) 2011-05-11 EP claimed
US-20100133519-A1 ARYLAMINE COMPOUNDS AND ELECTRONIC DEVICES AGENCY FOR SCIENCE, TECHNOLOGY ANR RESEARCH 2010-06-03 US claimed
WO-2010016990-A1 ORGANIC LIGHT-EMITTING DIODES FROM HOMOLEPTIC SQUARE PLANAR COMPLEXES UNIVERSITY OF NORTH TEXAS (US) 2010-02-11 WO claimed
EP-2121573-A1 ARYLAMINE COMPOUNDS AND ELECTRONIC DEVICES Agency for Science Technology and Research (SG) 2009-11-25 EP claimed
WO-2008069756-A1 ARYLAMINE COMPOUNDS AND ELECTRONIC DEVICES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2008-06-12 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12116378-B2 Transition metal luminescent complexes and methods of use OCIAD2, OCIAD1, OPRD1 NPC1 506/4885RAB9A 2855/4885GAA 3781/4885
US-20200176691-A1 TRANSITION METAL LUMINESCENT COMPLEXES AND METHODS OF USE OCIAD2, OCIAD1, OPRD1 NPC1 506/4885RAB9A 2855/4885GAA 3781/4885
US-20100133519-A1 ARYLAMINE COMPOUNDS AND ELECTRONIC DEVICES TYR, AHR, ARNT NPC1 709/4885RAB9A 2317/4885GAA 2258/4885
US-20220246865-A1 PEROVSKITE SOLAR CELLS BCL3, MCL1, ANXA3 NPC1 2585/4885RAB9A 602/4885GAA 4457/4885
US-12435100-B2 Perovskite solar cells BCL3, MCL1, ANXA3 NPC1 2585/4885RAB9A 602/4885GAA 4457/4885
US-20200172562-A1 TRANSITION METAL LUMINESCENT COMPLEXES AND METHODS OF USE OCIAD2, OCIAD1, OPRD1 NPC1 506/4885RAB9A 2855/4885GAA 3781/4885
US-20110260145-A1 ORGANIC LIGHT-EMITTING DIODES FROM HOMOLEPTIC SQUARE PLANAR COMPLEXES PTPRS, PTPRO, PTPRZ1 NPC1 4149/4885RAB9A 3429/4885GAA 4556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.