Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.62 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.62 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.56 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.55 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.54 |
| ▸ | THRA | P10827 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12327982 | 0.94 | CA5A (0.59) | PTPN11PTPN1PTPN6CA5APPARA | |
| SCHEMBL5093658 | 0.93 | PTPN11 (0.66) | PTPN11PTPN1PTPN6ALDH1A1S1PR2 | |
| SCHEMBL5138907 | 0.93 | PTPN11 (0.66) | PTPN11PTPN1PTPN6ALDH1A1S1PR2 | |
| SCHEMBL11435026 | 0.90 | CA5A (0.61) | PTPN11PTPN1PTPN6CA5APPARA | |
| SCHEMBL14823517 | 0.89 | GAA (0.59) | PTPN11PTPN1PTPN6CA5AGAA | |
| SCHEMBL9306444 | 0.88 | S1PR2 (0.55) | S1PR2S1PR1S1PR3LPAR2THRA | |
| SCHEMBL11579754 | 0.87 | PTPN11 (0.58) | PTPN11PTPN1PTPN6CA5AGAA | |
| SCHEMBL10461053 | 0.86 | CA5A (0.59) | CA5APPARAGAAALDH1A1TSHR | |
| SCHEMBL9306342 | 0.85 | S1PR2 (0.53) | S1PR2S1PR1S1PR3LPAR2THRA | |
| SCHEMBL4070157 | 0.84 | CA5A (0.61) | CA5APPARAGAAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5208247-A | Antianaphylactic agents or septic shock | AMERICAN CYANAMID COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0530444-A1 | Aryl, amide, imide, and carbamate pyridine antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |