Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 4/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.66 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.66 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.58 |
| ▸ | THRA | P10827 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5093658 | 1.00 | PTPN11 (0.66) | PTPN11PTPN1PTPN6PLA2G4BTHRA | |
| SCHEMBL11579754 | 0.94 | PTPN11 (0.58) | PTPN11PTPN1PTPN6PLA2G4BTHRA | |
| SCHEMBL9306902 | 0.93 | PTPN11 (0.62) | PTPN11PTPN1PTPN6PLA2G4BTHRA | |
| SCHEMBL28669480 | 0.89 | ALDH1A1 (0.53) | PTPN11PTPN1PTPN6THRATHRB | |
| SCHEMBL30159686 | 0.89 | ALDH1A1 (0.53) | PTPN11PTPN1PTPN6THRATHRB | |
| Hydrochloric Acid SCHEMBL10997417 | 0.88 | ALDH1A1 (0.51) | PTPN11PTPN1PTPN6ALDH1A1HPGD | |
| SCHEMBL9304941 | 0.87 | PTPN11 (0.62) | PTPN11PTPN1PTPN6PLA2G4BTHRA | |
| SCHEMBL12327982 | 0.87 | CA5A (0.59) | PTPN11PTPN1PTPN6THRATHRB | |
| SCHEMBL14823517 | 0.87 | GAA (0.59) | PTPN11PTPN1PTPN6THRATHRB | |
| SCHEMBL5090844 | 0.85 | SMPD1 (0.53) | PTPN11PTPN1PTPN6S1PR2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008047382-A2 | A PROCESS FOR THE PREPARATION OF 4-[2-[[3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]AMINO]ETHYL]-1,2-BENZENEDIOL | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2008-04-24 | — | — | WO | disclosed |