Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.55 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.55 |
| ▸ | THRA | P10827 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306902 | 0.88 | PTPN11 (0.62) | S1PR2S1PR1S1PR3LPAR2THRA | |
| SCHEMBL9309743 | 0.85 | ATM (0.56) | S1PR2S1PR1S1PR3LPAR2THRA | |
| SCHEMBL9306342 | 0.84 | S1PR2 (0.53) | S1PR2S1PR1S1PR3LPAR2THRA | |
| SCHEMBL10997415 | 0.83 | MAPT (0.50) | — | |
| SCHEMBL76377 | 0.82 | LMNA (0.59) | EPHX2 | |
| SCHEMBL12327982 | 0.82 | CA5A (0.59) | THRATHRB | |
| SCHEMBL2820207 | 0.81 | S1PR2 (0.57) | S1PR2S1PR1S1PR3LPAR2THRA | |
| SCHEMBL10427981 | 0.81 | S1PR2 (0.57) | S1PR2S1PR1S1PR3LPAR2THRA | |
| SCHEMBL579290 | 0.81 | S1PR2 (0.57) | S1PR2S1PR1S1PR3LPAR2THRA | |
| SCHEMBL2818338 | 0.81 | S1PR2 (0.54) | S1PR2S1PR1S1PR3LPAR2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5208247-A | Antianaphylactic agents or septic shock | AMERICAN CYANAMID COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0530444-A1 | Aryl, amide, imide, and carbamate pyridine antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |