Iodide

SCHEMBL9306978

CCCCCCCCCCCCCCOc1ccc(CC(=O)NCc2cc[n+](CC)cc2)cc1C(C)(C)C.[I-]

nearest known ligand 0.48

Known targets — ChEMBL curated mechanism

ACHE CHRM1 CHRM3 CHRNA1 CHRNB1 CHRND CHRNE CHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	HSD17B10	Q99714	1/20	0.44

▸	THRA	P10827	1/20	0.44

▸	THRB	P10828	1/20	0.44

▸	NPSR1	Q6W5P4	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Iodide SCHEMBL9308855	1.00	HSD17B10 (0.44)	HSD17B10THRATHRBNPSR1
Iodide SCHEMBL9307348	0.94	THRA (0.44)	HSD17B10THRATHRBNPSR1
Iodide SCHEMBL9305809	0.94	THRA (0.44)	HSD17B10THRATHRBNPSR1
Iodide SCHEMBL9306366	0.91	THRA (0.45)	THRATHRBNPSR1
Iodide SCHEMBL9309300	0.91	THRA (0.45)	THRATHRBNPSR1
Iodide SCHEMBL9305218	0.89	HSD17B10 (0.44)	HSD17B10THRATHRBNPSR1
Iodide SCHEMBL9307150	0.89	HSD17B10 (0.44)	HSD17B10THRATHRBNPSR1
Iodide SCHEMBL9308005	0.87	HSD17B10 (0.58)	HSD17B10NPSR1
Iodide SCHEMBL9307350	0.87	HSD17B10 (0.58)	HSD17B10NPSR1
Iodide SCHEMBL9309501	0.86	THRA (0.48)	THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5328921-A	Antagonist of platelet activating factor	AMERICAN CYANAMID COMPANY (US)	1994-07-12	—	—	US	disclosed