Acetophenone

Acetophenone

SCHEMBL9307347

CC(=O)c1ccccc1.CC(C)OC(C)C

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.54
SMN1; SMN2 Q16637 4/20 0.54
HPGD P15428 3/20 0.48
ALDH1A1 P00352 3/20 0.48
LMNA P02545 3/20 0.48
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
MAOB P27338 1/20 0.46
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
TAAR1 Q96RJ0 1/20 0.46
TSHR P16473 1/20 0.45
KMT2A Q03164 2/20 0.45
POLB P06746 1/20 0.45
HTT P42858 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
KDM4E B2RXH2 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
PDCD1 Q15116 1/20 0.44
CD274 Q9NZQ7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzil SCHEMBL28144200 0.84 CES2 (0.64) MAPTSMN1; SMN2HPGDALDH1A1LMNA
Benzophenone SCHEMBL9308337 0.84 ALDH1A1 (0.64) MAPTSMN1; SMN2HPGDALDH1A1LMNA
Acetophenone SCHEMBL28762993 0.84 MAPT (0.60) MAPTSMN1; SMN2HPGDALDH1A1LMNA
Acetophenone SCHEMBL10608667 0.84 MAPT (0.60) MAPTSMN1; SMN2HPGDALDH1A1LMNA
Acetophenone SCHEMBL28521015 0.83 SMN1; SMN2 (0.50) MAPTSMN1; SMN2HPGDALDH1A1LMNA
Acetophenone SCHEMBL737 0.83
Acetophenone SCHEMBL30537005 0.83
Acetophenone SCHEMBL30537000 0.83
Acetophenone SCHEMBL16745259 0.83
Acetophenone SCHEMBL1450855 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5331103-A Reaction with hydrogen peroxide, hydroquinone from phenol RHONE-POULENC CHIMIE (FR) 1994-07-19 US disclosed