Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 5/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5932070 | 0.89 | GABRA1 (0.52) | ALOX5ESR2GABRA1GABRB2ESR1 | |
| SCHEMBL27889218 | 0.89 | GABRA1 (0.53) | ALOX5ESR2GABRA1GABRB2ESR1 | |
| SCHEMBL9310538 | 0.87 | GABRA1 (0.48) | ALOX5ESR2GABRA1GABRB2ESR1 | |
| SCHEMBL29837102 | 0.85 | GABRA1 (0.48) | ALOX5ESR2GABRA1GABRB2ESR1 | |
| SCHEMBL5931905 | 0.85 | GABRA1 (0.48) | ALOX5ESR2GABRA1GABRB2ESR1 | |
| SCHEMBL10429707 | 0.82 | GABRA1 (0.52) | ALOX5GABRA1GABRB2AKR1B1BACE1 | |
| SCHEMBL29032545 | 0.81 | GABRA1 (0.47) | ALOX5ESR2GABRA1GABRB2ESR1 | |
| SCHEMBL2863552 | 0.81 | ALOX5 (0.65) | ALOX5ESR2ESR1CYP26A1BACE1 | |
| SCHEMBL10686699 | 0.81 | BACE1 (0.57) | ALOX5GABRA1GABRB2AKR1B1BACE1 | |
| Phenol SCHEMBL27952434 | 0.81 | GABRA1 (0.55) | ALOX5GABRA1GABRB2AKR1B1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344980-A | Process for the preparation of 1,3,5-tris(4'-hydroxyaryl)benzene | HOECHST CELANESE CORP. (US) | 1994-09-06 | — | — | US | disclosed |