Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.41 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27889218 | 0.92 | GABRA1 (0.53) | GABRA1GABRB2AKR1B1MEN1MAPT | |
| SCHEMBL28541485 | 0.85 | GABRA1 (0.47) | GABRA1GABRB2AKR1B1MEN1MAPT | |
| SCHEMBL5406886 | 0.85 | GABRA1 (0.55) | GABRA1GABRB2AKR1B1MEN1MAPT | |
| SCHEMBL27889219 | 0.84 | GABRA1 (0.56) | GABRA1GABRB2AKR1B1MEN1MAPT | |
| SCHEMBL27886719 | 0.82 | GABRA1 (0.47) | GABRA1GABRB2AKR1B1MEN1MAPT | |
| Biphenyl SCHEMBL7928631 | 0.82 | DPP4 (0.52) | GABRA1GABRB2AKR1B1KMT2AL3MBTL1 | |
| SCHEMBL9307517 | 0.82 | ALOX5 (0.53) | GABRA1GABRB2AKR1B1MEN1MAPT | |
| SCHEMBL31738460 | 0.82 | PSMB5 (0.39) | GABRA1GABRB2AKR1B1MEN1MAPT | |
| SCHEMBL170787 | 0.80 | DPP4 (0.54) | GABRA1GABRB2AKR1B1KMT2ADPP4 | |
| SCHEMBL2185735 | 0.80 | GABRA1 (0.82) | GABRA1GABRB2AKR1B1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360042-A1 | p-Terphenyl derivatives and liquid crystalline compositions | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1990-03-28 | — | — | EP | disclosed |