Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.82 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.82 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SRC | P12931 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mandelic Acid SCHEMBL7279536 | 0.91 | LMNA (0.90) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL1050 | 0.91 | LMNA (1.00) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL165161 | 0.91 | LMNA (1.00) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL29777368 | 0.91 | LMNA (1.00) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL255601 | 0.91 | LMNA (1.00) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL21647917 | 0.91 | LMNA (1.00) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL5313046 | 0.91 | LMNA (1.00) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL2689157 | 0.88 | LMNA (0.86) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL1275427 | 0.88 | LMNA (0.86) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL3934174 | 0.88 | LMNA (0.95) | LMNAMAPK1CES2CES1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326887-A | Reacting ester of alpha hydroxy acid oligomer over fixed bed catalyst | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-05 | — | — | US | disclosed |
| WO-1992015572-A1 | PROCESS FOR THE PREPARATION OF 1,4-DIOXANE-2,5-DIONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-17 | — | — | WO | disclosed |