SCHEMBL9307534

SCHEMBL9307534

COCCCNS(=O)(=O)c1ccccc1C

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.65
ALDH1A1 P00352 7/20 0.55
KDM4E B2RXH2 3/20 0.50
HPGD P15428 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
HTT P42858 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.48
GSTO1 P78417 1/20 0.47
POLB P06746 2/20 0.47
MAPT P10636 3/20 0.46
PKM P14618 2/20 0.46
RECQL P46063 1/20 0.46
TSHR P16473 1/20 0.46
CCR1 P32246 1/20 0.45
F13A1 P00488 1/20 0.45
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9308047 0.85 GAA (0.56) MAPK1ALDH1A1KDM4EHPGDSMN1; SMN2
SCHEMBL635553 0.82 CA12 (0.63) ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10
SCHEMBL31391062 0.82 CA12 (0.63) ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10
SCHEMBL9307250 0.81 ALDH1A1 (0.60) MAPK1ALDH1A1HPGDSMN1; SMN2HTT
SCHEMBL635207 0.81 RECQL (0.68) MAPK1ALDH1A1KDM4ESMN1; SMN2HTT
SCHEMBL6102760 0.80 SFRP1 (0.68) MAPK1ALDH1A1KDM4EHPGDSMN1; SMN2
SCHEMBL8355313 0.79 RECQL (0.70) MAPK1ALDH1A1KDM4ESMN1; SMN2HTT
SCHEMBL223155 0.79 RECQL (0.70) MAPK1ALDH1A1KDM4ESMN1; SMN2HTT
SCHEMBL7103283 0.79 RECQL (0.70) MAPK1ALDH1A1KDM4ESMN1; SMN2HTT
SCHEMBL634179 0.79 RECQL (0.70) MAPK1ALDH1A1KDM4ESMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200131335-A1 SURFACE ACTIVE ADJUVANT RHODIA OPERATIONS (FR) 2020-04-30 US disclosed
EP-3612604-A1 SURFACE ACTIVE ADJUVANT Rhodia Operations (FR) 2020-02-26 EP disclosed
WO-2020035124-A1 SURFACE ACTIVE ADJUVANT FOR COATINGS RHODIA OPERATIONS (FR) 2020-02-20 WO disclosed
CN-110536936-A Surface-active adjuvant RHODIA OPERATIONS 2019-12-03 CN disclosed
WO-2018193009-A1 SURFACE ACTIVE ADJUVANT RHODIA OPERATIONS (FR) 2018-10-25 WO disclosed
US-5328884-A Salicylic acid salt,and amide or sulfonamide as developer KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-07-12 US disclosed
US-5250108-A Mixture of salicylic acid salt, amide and sulfonamide compounds KANZAKI PAPER MANUFACTURING CO. LTD. (JP) 1993-10-05 US disclosed
US-4824721-A CAPSULES OF OIL SOLUBLE DYES WHICH SWELL AND RELEASE DYE UPON HEATING FUJI PHOTO FILM CO., LTD. (JP) 1989-04-25 US disclosed