Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | GYS1 | P13807 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | VHL | P40337 | 1/20 | 0.35 |
| ▸ | ELOC | Q15369 | 1/20 | 0.35 |
| ▸ | ELOB | Q15370 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308922 | 0.90 | HCRTR1 (0.42) | ATMPIK3CDMEN1KMT2APOLB | |
| SCHEMBL12261021 | 0.76 | MMP2 (0.46) | ATMPIK3CDMEN1KMT2AVHL | |
| SCHEMBL9034399 | 0.75 | HPGD (0.52) | MEN1KMT2ASCDMAPK1ALDH1A1 | |
| SCHEMBL19475011 | 0.75 | ATM (0.49) | ATMPIK3CDMEN1KMT2AKDM4E | |
| SCHEMBL2059307 | 0.74 | PIK3CD (0.65) | ATMPIK3CDALDH1A1HPGDACE | |
| SCHEMBL10470158 | 0.74 | ATM (0.47) | ATMPIK3CDMEN1KMT2APOLB | |
| SCHEMBL9307727 | 0.73 | ALDH1A1 (0.41) | ATMMEN1KMT2ASCDPOLB | |
| SCHEMBL9307737 | 0.73 | ALDH1A1 (0.41) | ATMMEN1KMT2ASCDPOLB | |
| SCHEMBL9309145 | 0.73 | ALDH1A1 (0.41) | ATMMEN1KMT2ASCDPOLB | |
| SCHEMBL341608 | 0.72 | GSK3B (0.42) | POLBMAPK1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332735-A | Antiamnesic activity | ADIR ET COMPAGNIE (FR) | 1994-07-26 | — | — | US | disclosed |