Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.39 |
| ▸ | WNT3A | P56704 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307568 | 0.90 | ATM (0.41) | HCRTR1HCRTR2ATMKDM4EPIK3CD | |
| SCHEMBL9308604 | 0.75 | ALDH1A1 (0.50) | ATMCTNNB1KDM4EMAPT | |
| SCHEMBL19475011 | 0.75 | ATM (0.49) | ATMKDM4EPIK3CDMEN1MAPT | |
| SCHEMBL2059307 | 0.74 | PIK3CD (0.65) | ATMPIK3CDMAPT | |
| SCHEMBL10470158 | 0.74 | ATM (0.47) | HCRTR1HCRTR2ATMPIK3CDMEN1 | |
| SCHEMBL12261021 | 0.73 | MMP2 (0.46) | HCRTR1HCRTR2ATMPIK3CDMEN1 | |
| SCHEMBL1020885 | 0.72 | CTNNB1 (0.52) | CTNNB1WNT3AKDM4EHDAC3HDAC4 | |
| SCHEMBL10469223 | 0.71 | PIK3CD (0.61) | ATMPIK3CDMEN1KMT2A | |
| SCHEMBL9028119 | 0.71 | PIK3CD (0.61) | ATMPIK3CDMEN1KMT2A | |
| SCHEMBL9028110 | 0.71 | PIK3CD (0.61) | ATMPIK3CDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332735-A | Antiamnesic activity | ADIR ET COMPAGNIE (FR) | 1994-07-26 | — | — | US | disclosed |