Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706171 | 0.77 | — | — | |
| SCHEMBL9304585 | 0.76 | TDP1 (0.53) | TDP1HPGDHSD17B10LMNAABCB11 | |
| SCHEMBL9304435 | 0.74 | TDP1 (0.65) | TDP1HPGDHSD17B10LMNAABCB11 | |
| SCHEMBL9305795 | 0.74 | TDP1 (0.50) | TDP1HPGDHSD17B10LMNAABCB11 | |
| SCHEMBL1165442 | 0.70 | — | — | |
| Succimer SCHEMBL28577215 | 0.69 | ALDH1A1 (1.00) | TDP1HPGDHSD17B10LMNAABCB11 | |
| Succimer SCHEMBL28566852 | 0.69 | ALDH1A1 (1.00) | TDP1HPGDHSD17B10LMNAABCB11 | |
| Succimer SCHEMBL14941 | 0.69 | ALDH1A1 (1.00) | TDP1HPGDHSD17B10LMNAABCB11 | |
| Succimer SCHEMBL14942 | 0.69 | ALDH1A1 (1.00) | TDP1HPGDHSD17B10LMNAABCB11 | |
| Succimer SCHEMBL17472961 | 0.69 | ALDH1A1 (1.00) | TDP1HPGDHSD17B10LMNAABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |