Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.61 |
| ▸ | GAA | P10253 | 8/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | CA12 | O43570 | 3/20 | 0.61 |
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | CA9 | Q16790 | 3/20 | 0.61 |
| ▸ | CA6 | P23280 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29476052 | 0.98 | KDM4E (0.64) | KDM4EGAAMAPTCA12CA1 | |
| SCHEMBL79989 | 0.98 | KDM4E (0.64) | KDM4EGAAMAPTCA12CA1 | |
| Hydrochloric Acid SCHEMBL8690817 | 0.96 | KDM4E (0.61) | KDM4EGAAMAPTCA12CA1 | |
| Hydrochloric Acid SCHEMBL9161193 | 0.94 | KDM4E (0.59) | KDM4EGAAMAPTCA12CA1 | |
| Phosphoric Acid SCHEMBL9468965 | 0.90 | KDM4E (0.55) | KDM4EGAAMAPTCA12CA1 | |
| SCHEMBL9306191 | 0.83 | KDM4E (0.61) | KDM4EGAAMAPTCA12CA1 | |
| SCHEMBL10434407 | 0.82 | HTT (0.65) | KDM4EGAAMAPTCA12CA1 | |
| SCHEMBL30786420 | 0.82 | ALDH1A1 (0.53) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL336990 | 0.82 | ALDH1A1 (0.53) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL2808434 | 0.82 | CDC25B (0.59) | KDM4EGAAMAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324808-A | Polybenzimidazoles, polybenzoazoles or polybenzothiazoles | THE DOW CHEMICAL COMPANY (US) | 1994-06-28 | — | — | US | disclosed |
| US-5235023-A | Forming polybenzimidazoles, polybenzthiazoles and polybenz-oxazoles; disodium or dilithium terephthalate monomer | THE DOW CHEMICAL COMPANY (US) | 1993-08-10 | — | — | US | disclosed |
| EP-0449811-A1 | IMPROVED PROCESS FOR SYNTHESIS OF HETEROCYCLIC POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1991-10-09 | — | — | EP | disclosed |
| WO-1990006960-A1 | IMPROVED PROCESS FOR SYNTHESIS OF HETEROCYCLIC POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1990-06-28 | — | — | WO | disclosed |