Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PEPD | P12955 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11649999 | 0.80 | PKM (0.35) | PKMSMN1; SMN2 | |
| SCHEMBL28766345 | 0.78 | LPAR2 (0.33) | — | |
| SCHEMBL7576649 | 0.76 | PKM (0.31) | PKMSMN1; SMN2 | |
| SCHEMBL16987216 | 0.74 | TSHR (0.33) | PKMSMN1; SMN2 | |
| SCHEMBL11308533 | 0.74 | BTN3A1 (0.31) | — | |
| SCHEMBL11681266 | 0.74 | MAPT (0.37) | PKMSMN1; SMN2 | |
| SCHEMBL18177935 | 0.72 | CYP3A4 (0.38) | PKMSMN1; SMN2 | |
| Methacrylic Acid SCHEMBL3464507 | 0.72 | FNTA (0.40) | PKMSMN1; SMN2PEPD | |
| SCHEMBL1443576 | 0.71 | PEPD (0.34) | PEPD | |
| SCHEMBL11682393 | 0.71 | ALDH1A1 (0.33) | PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601573-A1 | Alpha-phosphonocarboxylate squalene synthetase inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-15 | — | — | EP | disclosed |
| US-5312814-A | Antilipemic agents or anticholesterol agents | BRISTOL-MYERS SQUIBB CO. (US) | 1994-05-17 | — | — | US | disclosed |