SCHEMBL7576649

SCHEMBL7576649

C=CCOP(=O)(OCC=C)C(=CO)C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11649999 0.77 PKM (0.35) PKMSMN1; SMN2
SCHEMBL9307830 0.76 PKM (0.33) PKMSMN1; SMN2
SCHEMBL2987279 0.72 TSHR (0.35) PKMSMN1; SMN2
SCHEMBL16987216 0.71 TSHR (0.33) PKMSMN1; SMN2
SCHEMBL11681266 0.71 MAPT (0.37) PKMSMN1; SMN2
SCHEMBL28766345 0.70 LPAR2 (0.33)
SCHEMBL18177935 0.69 CYP3A4 (0.38) PKMSMN1; SMN2
SCHEMBL11682393 0.68 ALDH1A1 (0.33) PKMSMN1; SMN2
SCHEMBL11308533 0.67 BTN3A1 (0.31)
SCHEMBL3268744 0.67 LPAR2 (0.35) PKMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020107401-A1 Production of phosphonopyrazoles MONSNTO TECHNOLOGY LLC. 2002-08-08 US claimed
EP-1149108-A1 PRODUCTION OF PHOSPHONOPYRAZOLES Monsanto Co. (US) 2001-10-31 EP claimed
WO-2000046229-A1 PRODUCTION OF PHOSPHONOPYRAZOLES MONSANTO TECHNOLOGY LLC (US) 2000-08-10 WO claimed
US-20020107401-A1 Production of phosphonopyrazoles MONSNTO TECHNOLOGY LLC. 2002-08-08 US disclosed
EP-1149108-A1 PRODUCTION OF PHOSPHONOPYRAZOLES Monsanto Co. (US) 2001-10-31 EP disclosed
US-6297194-B1 INDUCING MALE STERILITY IN PLANTS BY TREATING PLANTS OR SEEDS WITH GAMETOCIDES MONSANTO TECHNOLOGY, LLC 2001-10-02 US disclosed
WO-2000046229-A1 PRODUCTION OF PHOSPHONOPYRAZOLES MONSANTO TECHNOLOGY LLC (US) 2000-08-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107401-A1 Production of phosphonopyrazoles PPIP5K2, PCK2, PFKFB4 PKM 828/4885SMN1; SMN2 4803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.