Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413550 | 0.88 | HTT (0.40) | HTTCA5AKDM4EPKMLMNA | |
| SCHEMBL9421955 | 0.85 | LMNA (0.62) | CA5AKDM4EPKMLMNAALDH1A1 | |
| SCHEMBL4373039 | 0.82 | ALDH1A1 (0.52) | HTTCA5AKDM4EPKMLMNA | |
| SCHEMBL17756673 | 0.82 | GABRA1 (0.41) | HTTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL9701610 | 0.81 | CYP3A4 (0.44) | HTTKDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL4117028 | 0.81 | HTT (0.67) | HTTCA5APKMLMNAALDH1A1 | |
| SCHEMBL11661828 | 0.81 | ALDH1A1 (0.41) | HTTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL11880085 | 0.81 | ALDH1A1 (0.41) | HTTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL11107375 | 0.81 | KDM4E (0.43) | KDM4EALDH1A1HPGDGABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL11664932 | 0.81 | ALDH1A1 (0.50) | HTTCA5AKDM4EPKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344980-A | Process for the preparation of 1,3,5-tris(4'-hydroxyaryl)benzene | HOECHST CELANESE CORP. (US) | 1994-09-06 | — | — | US | disclosed |
| US-5300698-A | Process for the prepartion of 1,3,5-tris(4'-hydroxyaryl)benzene | HOECHST CELANESE CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| WO-1993014053-A1 | PROCESS FOR THE PREPARATION OF 1,3,5-TRIS(4'-HYDROXYARYL)BENZENE | HOECHST CELANESE CORPORATION (US) | 1993-07-22 | — | — | WO | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |