Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.68 |
| ▸ | RAB9A | P51151 | 6/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105986 | 0.81 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 | |
| SCHEMBL30063475 | 0.81 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 | |
| SCHEMBL25252536 | 0.81 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 | |
| Hydrochloric Acid SCHEMBL11596610 | 0.79 | RAB9A (0.68) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 | |
| SCHEMBL11147962 | 0.79 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 | |
| SCHEMBL2031602 | 0.79 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 | |
| SCHEMBL6985206 | 0.79 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 | |
| SCHEMBL21708400 | 0.78 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 | |
| SCHEMBL14341709 | 0.78 | SMN1; SMN2 (0.66) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 | |
| SCHEMBL14501813 | 0.78 | SMN1; SMN2 (0.66) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0129506-B1 | HETEROCYCLICALLY SUBSTITUTED THIO(CYCLO)ALKANE POLYCARBOXYLIC ACIDS | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | disclosed |
| EP-0129506-A2 | Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |