Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL211024 | 0.86 | RAB9A (0.66) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9185252 | 0.85 | RAB9A (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL31132400 | 0.85 | RAB9A (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL4680538 | 0.85 | RAB9A (0.64) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| Bromide SCHEMBL10947640 | 0.85 | RAB9A (0.64) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL19029204 | 0.83 | HDAC6 (0.67) | NPC1RAB9AALDH1A1LMNACYP2D6 | |
| SCHEMBL10650359 | 0.81 | SMN1; SMN2 (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1121708 | 0.81 | CYP3A4 (0.57) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL31119848 | 0.81 | THRB (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL25252536 | 0.81 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103103586-B | The copper electroplating solution that contains thiazole compound | SHAANXI NORMAL UNIVERSITY (CN) | 2016-05-04 | — | — | CN | claimed |
| CN-103103586-A | Thiazole compound-containing copper electroplating solution | UNIV SHAANXI NORMAL | 2013-05-15 | — | — | CN | claimed |
| EP-4400505-A1 | PEPTIDE-UREA DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND APPLICATION THEREOF | Bivision Pharmaceuticals, Inc (CN) | 2024-07-17 | — | — | EP | disclosed |
| CN-107892823-B | One kind is suitable for the anhydrous woolen dyed disperse dyes and preparation method thereof of supercritical carbon dioxide with azobenzthiazole structure | DALIAN POLYTECHNIC UNIVERSITY (CN) | 2019-10-29 | — | — | CN | disclosed |
| US-20180312493-A1 | Antibiotic Compounds, Pharmaceutical Formulations Thereof And Methods And Uses Therefor | CENTRE FOR DRUG RESEARCH AND DEVELOPMENT (CA) | 2018-11-01 | — | — | US | disclosed |
| CN-107892823-A | One kind is suitable for anhydrous woolen dyed disperse dyes of supercritical carbon dioxide and preparation method thereof with azobenzthiazole structure | 大连工业大学 | 2018-04-10 | — | — | CN | disclosed |
| CN-103103586-B | The copper electroplating solution that contains thiazole compound | SHAANXI NORMAL UNIVERSITY (CN) | 2016-05-04 | — | — | CN | disclosed |
| CN-103103586-A | Thiazole compound-containing copper electroplating solution | UNIV SHAANXI NORMAL | 2013-05-15 | — | — | CN | disclosed |
| EP-1177194-B1 | 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS | BASF AG (DE) | 2003-09-17 | — | — | EP | disclosed |
| US-6589915-B1 | The invention relates to cyclohexenone derivatives of benzo-condensed, unsaturated 5-ring nitrogen heterocycles of general formula (I) wherein X represents N or a group C-R3, Y represents O, S, SO, SO2 or NR4 or X-Y represent S | BASF AKTIENGESELLSCHAFT (DE) | 2003-07-08 | — | — | US | disclosed |
| US-6541423-B1 | Controlling vegatation | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-01 | — | — | US | disclosed |
| EP-1177179-A1 | BENZOHETERO CYCLYLCYCLO HEXENONES AND THEIR USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-06 | — | — | EP | disclosed |
| EP-1177194-A1 | 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000068228-A1 | 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-16 | — | — | WO | disclosed |
| WO-2000068210-A1 | BENZOHETERO CYCLYLCYCLO HEXENONES AND THEIR USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180312493-A1 | Antibiotic Compounds, Pharmaceutical Formulations Thereof And Methods And Uses Therefor | UGT1A8, CYP2C8, CXCL8 | NPC1 52/4885RAB9A 663/4885SMN1; SMN2 4665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.