SCHEMBL9308033

SCHEMBL9308033

CC(C)(C)c1ccc(C(C)(C)C)c([CH]c2cc(C(C)(C)C)ccc2C(C)(C)C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ALDH1A1 P00352 4/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MEN1 O00255 2/20 0.38
GAA P10253 2/20 0.38
PKM P14618 2/20 0.38
KMT2A Q03164 2/20 0.38
RECQL P46063 1/20 0.38
NR1I2 O75469 1/20 0.38
TSHR P16473 1/20 0.37
SCN10A Q9Y5Y9 2/20 0.37
KCNH2 Q12809 1/20 0.37
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
TYR P14679 1/20 0.36
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1798644 0.83 MAPT (0.42) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL29630132 0.75 ALDH1A1 (0.48) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL779415 0.75 ALDH1A1 (0.48) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL3415979 0.74 TSHR (0.44) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL21288350 0.73 TSHR (0.48) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL676421 0.73 ALDH1A1 (0.41) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL1447610 0.71 KLF10 (0.47) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL585667 0.70 ALDH1A1 (0.43) MAPTALDH1A1HPGDALOX15HSD17B10
SCHEMBL2146967 0.70 ALDH1A1 (0.43) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL1694994 0.70 ALDH1A1 (0.43) MAPTSMN1; SMN2ALDH1A1HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5324604-A Multi-active electrophotographic element and imaging process using free radicals as charge transport material EASTMAN KODAK COMPANY (US) 1994-06-28 US claimed
US-5324604-A Multi-active electrophotographic element and imaging process using free radicals as charge transport material EASTMAN KODAK COMPANY (US) 1994-06-28 US disclosed