Iodide

SCHEMBL9308348

CCCCCCCCCCCCCCOc1ccc(CN(Cc2cccc[n+]2CCC)C(=O)c2ccccc2OC)cc1OC.[I-]

nearest known ligand 0.56

Known targets — ChEMBL curated mechanism

ACHE CHRM1 CHRM3 CHRNA1 CHRNB1 CHRND CHRNE CHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	LMNA	P02545	1/20	0.41

▸	MAPT	P10636	1/20	0.41

▸	HTT	P42858	1/20	0.41

▸	SMN1; SMN2	Q16637	1/20	0.41

▸	L3MBTL1	Q9Y468	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Iodide SCHEMBL9306807	0.93	ATM (0.38)	—
Iodide SCHEMBL9307740	0.92	—	—
Iodide SCHEMBL9308402	0.91	—	—
Iodide SCHEMBL9305092	0.90	—	—
Iodide SCHEMBL9305821	0.88	MAPT (0.44)	LMNAMAPTHTTSMN1; SMN2L3MBTL1
Iodide SCHEMBL9308519	0.86	—	—
Iodide SCHEMBL9308427	0.85	LMNA (0.42)	LMNAMAPTHTTSMN1; SMN2L3MBTL1
Iodide SCHEMBL9306446	0.85	—	—
Iodide SCHEMBL9306347	0.85	LMNA (0.44)	LMNAMAPTHTTSMN1; SMN2L3MBTL1
Iodide SCHEMBL9307100	0.85	THRA (0.45)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5328921-A	Antagonist of platelet activating factor	AMERICAN CYANAMID COMPANY (US)	1994-07-12	—	—	US	disclosed