Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | GAPDH | P04406 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308423 | 0.89 | INPPL1 (0.49) | PTPN5ADRA2AADRA2BADRA2CHSD17B1 | |
| SCHEMBL9307755 | 0.87 | TDP2 (0.43) | PTPN5ADRA2AADRA2BADRA2CHSD17B1 | |
| SCHEMBL473246 | 0.80 | TDP1 (0.44) | — | |
| SCHEMBL8048666 | 0.78 | SELL (0.45) | ADRA2AADRA2BADRA2CHSD17B1HSD17B2 | |
| SCHEMBL1029074 | 0.77 | HTR7 (0.55) | PTPN5ADRA2AADRA2BADRA2CCYP3A4 | |
| SCHEMBL9308174 | 0.77 | INPPL1 (0.55) | PTPN5SRCPTGER1PTGER4PTGER3 | |
| SCHEMBL8048670 | 0.77 | SELL (0.47) | ADRA2AADRA2BADRA2CHSD17B1HSD17B2 | |
| SCHEMBL9307758 | 0.76 | INPPL1 (0.46) | PTPN5HSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL20573260 | 0.75 | SELL (0.43) | ADRA2AADRA2BADRA2CHSD17B1HSD17B2 | |
| SCHEMBL4779452 | 0.75 | HSD17B1 (0.64) | HSD17B1HSD17B2CYP3A4CYP2C9GAPDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5278212-A | Hydroxy phenyl organo phosphorus compound | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-01-11 | — | — | US | disclosed |