Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20689342 | 0.80 | SMN1; SMN2 (0.46) | TSHRTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL10067952 | 0.76 | NPC1 (0.40) | TSHRTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL10037297 | 0.76 | TSHR (0.39) | TSHRTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL358337 | 0.72 | — | — | |
| SCHEMBL9311809 | 0.71 | KDM6B (0.39) | NPC1RAB9AL3MBTL1GAAKDM4C | |
| SCHEMBL28222867 | 0.70 | — | — | |
| SCHEMBL5134164 | 0.70 | IL1B (0.45) | TSHRTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8988198 | 0.69 | PDPK1 (0.59) | TSHRTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11395584 | 0.68 | CDK2 (0.43) | TSHRALDH1A1PDPK1RAB9ACHEK1 | |
| SCHEMBL20929048 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62138474-A | — | — | None | — | — | JP | disclosed |
| US-5284958-A | Acylation, cyclization of a 5-hydrazine-1H-pyrazole | FUJI PHOTO FILM CO., LTD. (JP) | 1994-02-08 | — | — | US | disclosed |
| US-5214149-A | Process for producing a 1H-pyrazolo[5,1-c]-1,2,4-triazole compound | FUJI PHOTO FILM CO., LTD. (JP) | 1993-05-25 | — | — | US | disclosed |
| US-5055587-A | One-step, high yields | FUJI PHOTO FILM CO., LTD. (JP) | 1991-10-08 | — | — | US | disclosed |
| JP-S62138474-A | PRODUCTION OF 5-HYDRAZINOPYRAZOLE-4-CARBOXYLATE COMPOUND | KONISHIROKU PHOTO IND CO LTD | 1987-06-22 | — | — | JP | disclosed |