Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309615 | 0.93 | HPGD (0.51) | TSHRHPGDSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL9308604 | 0.89 | ALDH1A1 (0.50) | TSHRHPGDRECQLSMN1; SMN2CHRNA7 | |
| SCHEMBL9308546 | 0.84 | MEN1 (0.53) | TSHRHPGDRECQLSMN1; SMN2CHRNA7 | |
| SCHEMBL9034399 | 0.81 | HPGD (0.52) | TSHRHPGDSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL9310714 | 0.77 | HPGD (0.62) | TSHRHPGDSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9028847 | 0.76 | MMP2 (0.50) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9028843 | 0.76 | MMP2 (0.50) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL21697319 | 0.76 | MMP2 (0.50) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9308729 | 0.75 | HPGD (0.58) | TSHRHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL9029299 | 0.71 | SMN1; SMN2 (0.54) | HPGDSMN1; SMN2ALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332735-A | Antiamnesic activity | ADIR ET COMPAGNIE (FR) | 1994-07-26 | — | — | US | disclosed |