Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308857 | 0.92 | PPARG (0.46) | PPARG | |
| SCHEMBL9310836 | 0.84 | PPARG (0.40) | PPARG | |
| SCHEMBL9254113 | 0.82 | PPARG (0.39) | PPARGGABRA1GABRG2GABRB3GABRA2 | |
| SCHEMBL9310965 | 0.80 | PPARG (0.40) | PPARG | |
| SCHEMBL9308412 | 0.78 | AGTR1 (0.58) | PPARG | |
| SCHEMBL9309802 | 0.78 | ADORA3 (0.41) | — | |
| SCHEMBL9310075 | 0.77 | PPARG (0.45) | PPARG | |
| SCHEMBL1894719 | 0.77 | KDM4E (0.40) | PPARG | |
| SCHEMBL9308991 | 0.77 | — | — | |
| SCHEMBL9253827 | 0.76 | PPARG (0.41) | PPARGGABRA1GABRG2GABRB3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358950-A | Useful in treatment of cardiovascular diseases | LABORATOIRES UPSA (FR) | 1994-10-25 | — | — | US | disclosed |