Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.47 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | F9 | P00740 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9126457 | 0.87 | PPARA (0.54) | PPARAPPARGGCGRF9F10 | |
| SCHEMBL9051395 | 0.82 | GCGR (0.49) | PPARAPPARGGCGRF9F10 | |
| SCHEMBL9307429 | 0.77 | PPARA (0.53) | PPARAPPARG | |
| SCHEMBL9128765 | 0.77 | PPARA (0.53) | PPARAPPARGGCGRF9F10 | |
| SCHEMBL9063509 | 0.76 | F9 (0.41) | PPARAPPARGF9F10PLAU | |
| SCHEMBL9308098 | 0.76 | EDNRB (0.57) | EDNRA | |
| SCHEMBL13924239 | 0.75 | ALDH1A1 (0.44) | F9F10ALDH1A1KMT2AKDM4E | |
| SCHEMBL4016793 | 0.74 | L3MBTL1 (0.41) | PPARAPPARGGCGRF9F10 | |
| SCHEMBL9129828 | 0.73 | ALDH1A1 (0.47) | PPARAPPARGGCGRF9F10 | |
| SCHEMBL9159728 | 0.71 | PPARG (0.50) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374638-A | Cardiovascular disorders, hypotensive agents | MERCK & CO., INC. (US) | 1994-12-20 | — | — | US | disclosed |