Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11643170 | 0.87 | PABPC1 (0.51) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 | |
| SCHEMBL9340624 | 0.86 | ALDH1A1 (0.49) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 | |
| SCHEMBL23664923 | 0.86 | ALDH1A1 (0.49) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 | |
| SCHEMBL27477569 | 0.86 | ALDH1A1 (0.49) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 | |
| SCHEMBL9308294 | 0.84 | PABPC1 (0.46) | PABPC1APOBEC3AAPOBEC3GPTGS2ALDH1A1 | |
| SCHEMBL6913601 | 0.84 | HDAC3 (0.50) | TBXAS1TBXA2RHDAC3HDAC4HDAC1 | |
| SCHEMBL6913607 | 0.84 | HDAC3 (0.50) | TBXAS1TBXA2RHDAC3HDAC4HDAC1 | |
| SCHEMBL9419401 | 0.83 | FFAR4 (0.49) | HDAC11ALDH1A1FFAR4 | |
| SCHEMBL6666615 | 0.83 | PABPC1 (0.50) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 | |
| SCHEMBL4392102 | 0.81 | CYSLTR2 (0.44) | TBXAS1HDAC11ALDH1A1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304658-A | Quinone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| US-5180742-A | Lipoxygenase Inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0171251-B2 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-12-23 | — | — | EP | disclosed |
| EP-0171251-B1 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0171251-A2 | Quinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-02-12 | — | — | EP | disclosed |