Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4448852 | 0.92 | MMP12 (0.43) | PABPC1APOBEC3AAPOBEC3GPTGS2 | |
| SCHEMBL9389062 | 0.88 | PABPC1 (0.50) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 | |
| SCHEMBL27477569 | 0.85 | ALDH1A1 (0.49) | PABPC1APOBEC3AAPOBEC3GNPC1RAB9A | |
| SCHEMBL9340624 | 0.85 | ALDH1A1 (0.49) | PABPC1APOBEC3AAPOBEC3GNPC1RAB9A | |
| SCHEMBL9309152 | 0.84 | TBXAS1 (0.49) | PABPC1APOBEC3AAPOBEC3GPTGS2ALDH1A1 | |
| SCHEMBL6666615 | 0.81 | PABPC1 (0.50) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 | |
| SCHEMBL10944021 | 0.81 | PTGS2 (0.44) | PTGS2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1839792 | 0.80 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL1835818 | 0.80 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL1836560 | 0.80 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304658-A | Quinone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| US-5180742-A | Lipoxygenase Inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0171251-B2 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-12-23 | — | — | EP | disclosed |
| CN-1012495-B | Preparation method and application of benzoquinone derivative | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1991-05-01 | — | — | CN | disclosed |
| EP-0171251-B1 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-06-27 | — | — | EP | disclosed |
| CN-85105976-A | The preparation method of quinone derivatives and purposes | — | 1986-10-22 | — | — | CN | disclosed |
| EP-0171251-A2 | Quinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-02-12 | — | — | EP | disclosed |