Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3095401 | 0.81 | FAAH (0.39) | MGLLGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6052596 | 0.81 | MGLL (0.39) | NOTUMMGLLTUBB4ATUBBTUBA3C | |
| SCHEMBL7016863 | 0.81 | CYP2A6 (0.50) | NOTUMMGLLTUBB4ATUBBTUBA3C | |
| SCHEMBL5126021 | 0.81 | FAAH (0.39) | HSD17B10MGLLGRIA1GRIA2GRIA3 | |
| SCHEMBL5126073 | 0.80 | IDO1 (0.47) | HSD17B10NOTUMMGLLTUBB4ATUBB | |
| SCHEMBL1680730 | 0.80 | COMT (0.48) | MGLLTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6630210 | 0.78 | MEN1 (0.43) | MGLLGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL14395511 | 0.77 | BCHE (0.39) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 | |
| SCHEMBL4118733 | 0.77 | GRIA1 (0.46) | GRIA1GRIA2GRIA3GRIA4HDAC2 | |
| SCHEMBL5129468 | 0.77 | HDAC2 (0.37) | NOTUMGRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242426-B1 | GAMMA-HYDROXY-2-(FLUOROALKYLAMINOCARBONYL)-1-PIPERAZINEPENTANAMIDES AS HIV PROTEASE INHIBITORS | MERCK & CO INC (US) | 2007-10-31 | — | — | EP | disclosed |
| US-5366984-A | Fungicides, insecticides | BASF AKTIENGESELLSCHAFT (DE) | 1994-11-22 | — | — | US | disclosed |
| US-5294628-A | Fungicides, insecticides, pesticides | BASF AKTIENGESELLSCHAFT (DE) | 1994-03-15 | — | — | US | disclosed |
| EP-0378755-B1 | Heterocyclically substituted alpha-aryl acryl acid methyl esters and their use | BASF AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| US-5250553-A | Fungicides; pesticides | BASF AKTIENGESELLSCHAFT (DE) | 1993-10-05 | — | — | US | disclosed |
| US-5166216-A | Fungicides, pesticides, insecticides | BASF AKTIENGESELLSCHAFT (DE) | 1992-11-24 | — | — | US | disclosed |
| EP-0378755-A1 | Heterocyclically substituted alpha-aryl acryl acid methyl esters and their use | BASF Aktiengesellschaft (DE) | 1990-07-25 | — | — | EP | disclosed |