Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 3/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9310427 | 0.78 | DUT (0.38) | DUTNT5E | |
| SCHEMBL442714 | 0.77 | SLC28A1 (0.43) | — | |
| SCHEMBL6328518 | 0.75 | DUT (0.50) | DUTNT5ECYP3A4CYP2C9 | |
| SCHEMBL9174049 | 0.73 | DUT (0.33) | DUTNT5ECYP3A4CYP2C9 | |
| SCHEMBL443437 | 0.73 | DUT (0.35) | DUTNT5ECYP3A4CYP2C9 | |
| SCHEMBL9176009 | 0.72 | NT5E (0.38) | DUTNT5E | |
| SCHEMBL9738791 | 0.72 | DUT (0.38) | DUTNT5ECYP3A4CYP2C9 | |
| SCHEMBL9494704 | 0.67 | DUT (0.31) | DUT | |
| SCHEMBL5486401 | 0.67 | LMNA (0.46) | HSP90AA1 | |
| SCHEMBL442715 | 0.66 | P2RY14 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316017-B1 | 2',3'-Dideoxy-2'-fluoronucleosides | BRISTOL MYERS SQUIBB CO (US) | 1994-01-19 | — | — | EP | disclosed |
| US-5218106-A | From 2'-doexy-2'-fluoronucleosides; viricides | BRISTOL-MYERS COMPANY (US) | 1993-06-08 | — | — | US | disclosed |
| US-4908440-A | 2',3'-dideoxy-2'-fluoroarabinopyrimidine nucleosides | BRISTOL MYERS COMPANY (US) | 1990-03-13 | — | — | US | disclosed |