Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TK1 | P04183 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9310069 | 0.91 | TK1 (0.60) | LMNASMN1; SMN2TK1MAPTESR1 | |
| SCHEMBL600417 | 0.86 | LMNA (0.52) | LMNASMN1; SMN2TK1MAPTESR1 | |
| SCHEMBL600418 | 0.86 | LMNA (0.52) | LMNASMN1; SMN2TK1MAPTESR1 | |
| SCHEMBL600416 | 0.86 | LMNA (0.52) | LMNASMN1; SMN2TK1MAPTESR1 | |
| SCHEMBL9308235 | 0.83 | TK1 (0.52) | LMNATK1 | |
| SCHEMBL9308657 | 0.83 | TK1 (0.74) | LMNASMN1; SMN2TK1TSHRPMP22 | |
| SCHEMBL599760 | 0.81 | LMNA (0.56) | LMNASMN1; SMN2TK1MAPTESR1 | |
| SCHEMBL599759 | 0.81 | LMNA (0.56) | LMNASMN1; SMN2TK1MAPTESR1 | |
| SCHEMBL9311378 | 0.80 | LMNA (0.62) | LMNASMN1; SMN2TK1MAPTESR1 | |
| SCHEMBL9308597 | 0.80 | LMNA (0.49) | LMNASMN1; SMN2TK1MAPTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374625-A | Bis/hydroxymethyl/cycloalkyl derivatives; viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0468352-A2 | Novel nucleic acid derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-01-29 | — | — | EP | disclosed |