Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 6/20 | 0.74 |
| ▸ | PYGM | P11217 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9310751 | 0.91 | TK1 (0.86) | TK1PYGMLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL3411580 | 0.85 | TK1 (1.00) | TK1PYGMLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL13314168 | 0.85 | TK1 (1.00) | TK1PYGMLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL10659809 | 0.85 | TK1 (1.00) | TK1PYGMLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL3411578 | 0.85 | TK1 (1.00) | TK1PYGMLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL9309488 | 0.83 | LMNA (0.53) | TK1LMNASMN1; SMN2TSHRPMP22 | |
| SCHEMBL9308235 | 0.83 | TK1 (0.52) | TK1LMNABLMADRA1A | |
| SCHEMBL9309616 | 0.81 | TK1 (0.77) | TK1CYP1A2BLMCYP3A4TSHR | |
| SCHEMBL9309443 | 0.80 | TK1 (0.73) | TK1PYGMLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL9308908 | 0.80 | TK1 (0.57) | TK1PYGMCYP1A2BLMCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374625-A | Bis/hydroxymethyl/cycloalkyl derivatives; viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0468352-A2 | Novel nucleic acid derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-01-29 | — | — | EP | disclosed |