SCHEMBL9309591

SCHEMBL9309591

CC(C)c1c(Oc2ccccc2)cc(N)c(N)c1C(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
GAA P10253 2/20 0.39
ALDH1A1 P00352 1/20 0.39
ADORA2A P29274 1/20 0.39
MAOB P27338 1/20 0.38
RCE1 Q9Y256 1/20 0.38
MAOA P21397 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
BRD4 O60885 1/20 0.37
LTA4H P09960 1/20 0.35
TSHR P16473 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
NLRP3 Q96P20 1/20 0.35
HRH1 P35367 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30561268 0.74 CYP1A2 (0.52) CYP1A2CYP3A4CYP2C9CYP2C19GAA
SCHEMBL679994 0.74 CYP1A2 (0.52) CYP1A2CYP3A4CYP2C9CYP2C19GAA
SCHEMBL2210191 0.74 CYP1A2 (0.47) CYP1A2CYP3A4CYP2C9CYP2C19GAA
SCHEMBL6619121 0.72 LTA4H (0.46) GAAALDH1A1LTA4HTSHRKMT2A
SCHEMBL8030933 0.72 CYP1A2 (0.62) CYP1A2CYP3A4CYP2C9CYP2C19GAA
SCHEMBL4456664 0.70 CYP1A2 (0.47) CYP1A2CYP3A4CYP2C9CYP2C19GAA
SCHEMBL2943595 0.70 CYP1A2 (0.56) CYP1A2CYP3A4CYP2C9CYP2C19GAA
Hydrochloric Acid SCHEMBL10423775 0.70 CYP1A2 (0.60) CYP1A2CYP3A4CYP2C9CYP2C19GAA
SCHEMBL22185237 0.70 SLC6A4 (0.41) CYP1A2LTA4HTSHRHRH1PTGS1
SCHEMBL11692589 0.69 TTR (0.53) CYP1A2CYP3A4CYP2C9CYP2C19GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0362649-B1 Radiation-sensitive compositions and their use BASF AG (DE) 1994-03-02 EP claimed
US-5284734-A Insulating layers and printed circuits; precursors for polyimides and polyquinazolines BASF AKTIENGESELLSCHAFT (DE) 1994-02-08 US claimed
US-5284734-A Insulating layers and printed circuits; precursors for polyimides and polyquinazolines BASF AKTIENGESELLSCHAFT (DE) 1994-02-08 US disclosed