SCHEMBL9309599

SCHEMBL9309599

CCOC(=O)c1c(C)nc(CC)n1Cc1ccc2oc(-c3ccccc3C(=O)O)c(Br)c2c1

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9309360 0.93 AGTR1 (0.51) AGTR1
SCHEMBL9309028 0.92 AGTR1 (0.54) AGTR1
SCHEMBL9429563 0.90 AGTR1 (0.47) AGTR1
SCHEMBL9309893 0.89 AGTR1 (0.48) AGTR1
SCHEMBL9309392 0.89 AGTR1 (0.51) AGTR1
SCHEMBL9308867 0.87 AGTR1 (0.49) AGTR1
SCHEMBL7299689 0.85 AGTR1 (0.69) AGTR1
SCHEMBL9309342 0.85 AGTR1 (0.42) AGTR1
SCHEMBL9309257 0.84 AGTR1 (0.51) AGTR1
Hydrochloric Acid SCHEMBL9310039 0.84 AGTR1 (0.51) AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5374646-A Treatment or prophylasix of hypertension and diseases associated with cognitive disorders GLAXO GROUP LIMITED (GB) 1994-12-20 US disclosed