Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309751 | 0.88 | ESR2 (0.42) | PPARGCNR2PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL9309094 | 0.85 | PPARG (0.36) | PPARGCNR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1889453 | 0.81 | KDM4E (0.41) | PPARGCNR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9308998 | 0.80 | KDM4E (0.37) | PPARGCNR2CYP2C9CYP2C19PRKAG1 | |
| SCHEMBL1894428 | 0.79 | PPARG (0.50) | PPARGACHE | |
| SCHEMBL1890638 | 0.78 | CCR2 (0.39) | PPARGCNR2CYP2C9CYP2C19ACHE | |
| SCHEMBL9309290 | 0.77 | PPARG (0.46) | PPARGACHE | |
| SCHEMBL9311500 | 0.76 | AGTR1 (0.49) | CYP2C9CYP2C19DPP4 | |
| SCHEMBL9309001 | 0.75 | CNR1 (0.41) | PPARGCNR2CYP2C9CYP2C19AKT1 | |
| SCHEMBL9311340 | 0.72 | PPARG (0.49) | PPARGESR2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358950-A | Useful in treatment of cardiovascular diseases | LABORATOIRES UPSA (FR) | 1994-10-25 | — | — | US | disclosed |