Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | UGCG | Q16739 | 1/20 | 0.35 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309824 | 0.88 | PPARG (0.40) | ESR2PPARGCNR2FFAR1AKR1B1 | |
| SCHEMBL9309094 | 0.85 | PPARG (0.36) | ESR2PPARGCNR2OXTRAVPR1A | |
| SCHEMBL9309571 | 0.81 | ESR2 (0.45) | ESR2PPARGFFAR1AKR1B1MYC | |
| SCHEMBL1889453 | 0.80 | KDM4E (0.41) | PPARGCNR2 | |
| SCHEMBL9307715 | 0.80 | PPARG (0.49) | ESR2PPARGAGTR1AGTR2 | |
| SCHEMBL9308998 | 0.79 | KDM4E (0.37) | PPARGCNR2PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL9308844 | 0.78 | PPARG (0.45) | ESR2PPARGAGTR1AGTR2 | |
| SCHEMBL1890638 | 0.77 | CCR2 (0.39) | PPARGCNR2 | |
| SCHEMBL1890018 | 0.75 | ESR2 (0.45) | ESR2PPARGFFAR1AKR1B1MYC | |
| SCHEMBL9311500 | 0.75 | AGTR1 (0.49) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358950-A | Useful in treatment of cardiovascular diseases | LABORATOIRES UPSA (FR) | 1994-10-25 | — | — | US | disclosed |