Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1780110 | 0.82 | DRD2 (0.58) | DRD2DRD3TAAR1ALDH1A1TRPM8 | |
| Hydrochloric Acid SCHEMBL1780107 | 0.81 | DRD2 (0.56) | DRD2DRD3TAAR1ALDH1A1TRPM8 | |
| SCHEMBL9281325 | 0.73 | TAAR1 (0.52) | DRD2DRD3TAAR1ALDH1A1TRPM8 | |
| SCHEMBL5270807 | 0.71 | TAAR1 (0.48) | DRD2DRD3TAAR1ALDH1A1TRPM8 | |
| SCHEMBL10937071 | 0.71 | DRD2 (0.49) | DRD2DRD3TAAR1ALDH1A1TRPM8 | |
| SCHEMBL7073867 | 0.70 | DRD2 (0.43) | DRD2DRD3TAAR1NPC1ALDH1A1 | |
| SCHEMBL7005198 | 0.69 | RIPK1 (0.43) | DRD2DRD3TAAR1ALDH1A1TRPM8 | |
| SCHEMBL2376616 | 0.68 | TAAR1 (0.54) | DRD2DRD3TAAR1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL8094705 | 0.68 | NPC1 (0.45) | TAAR1NPC1ALDH1A1POLBKDM4E | |
| Hydrochloric Acid SCHEMBL4599895 | 0.67 | KDM4E (0.53) | DRD2DRD3TAAR1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342953-A | N-2-chlorobenzyl-2-oxo and N-2-chlorobenzyl-2,2-dioxo-1,2,3-oxathiazolidine derivatives, their preparation and synthesis of thieno[3,2-c]pyridine derivatives therefrom | SYNTEX (U.S.A.) INC. (US) | 1994-08-30 | — | — | US | disclosed |