SCHEMBL1780110

SCHEMBL1780110

CCN(CC)CCc1cccs1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.58
DRD3 P35462 1/20 0.58
TAAR1 Q96RJ0 1/20 0.50
TRPM8 Q7Z2W7 4/20 0.42
HSD11B1 P28845 1/20 0.42
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
ADRA2A P08913 3/20 0.42
ADRA2B P18089 3/20 0.42
ADRA2C P18825 2/20 0.42
RIPK1 Q13546 1/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MAPK1 P28482 1/20 0.41
RECQL P46063 1/20 0.41
GFER P55789 1/20 0.41
CYP1A2 P05177 1/20 0.39
CHRM2 P08172 1/20 0.39
CHRM5 P08912 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1780107 0.98 DRD2 (0.56) DRD2DRD3TAAR1TRPM8HSD11B1
SCHEMBL9281325 0.89 TAAR1 (0.52) DRD2DRD3TAAR1TRPM8PTGS1
SCHEMBL5270807 0.83 TAAR1 (0.48) DRD2DRD3TAAR1TRPM8RIPK1
SCHEMBL10937071 0.82 DRD2 (0.49) DRD2DRD3TAAR1TRPM8HSD11B1
SCHEMBL9309832 0.82 DRD2 (0.47) DRD2DRD3TAAR1TRPM8HSD11B1
SCHEMBL2376616 0.79 TAAR1 (0.54) DRD2DRD3TAAR1HSD11B1PTGS1
Hydrochloric Acid SCHEMBL4599895 0.78 KDM4E (0.53) DRD2DRD3TAAR1HSD11B1PTGS1
SCHEMBL21034335 0.77 DRD2 (0.55) DRD2DRD3TAAR1HSD11B1PTGS2
SCHEMBL7005198 0.77 RIPK1 (0.43) DRD2DRD3TAAR1TRPM8HSD11B1
SCHEMBL151464 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110118357-A1 PROCESS FOR PREPARING O-DESMETHYLVENLAFAXINE GENERICS LIMITED 2011-05-19 US claimed
EP-2200968-A1 PROCESS FOR PREPARING O-DESMETHYLVENLAFAXINE Generics Ýuk¨Limited (GB) 2010-06-30 EP claimed
WO-2009053731-A1 PROCESS FOR PREPARING O-DESMETHYLVENLAFAXINE GENERICS [UK] LIMITED (GB) 2009-04-30 WO claimed
EP-0136649-B1 PROCESS FOR THE PREPARATION OF CATIONIC VINYL ESTER BASED POLYMER LATICES AND THEIR USE AS FORMALDEHYDE-FREE BINDERS. National Starch and Chemical Corporation (US) 1989-11-15 EP claimed
US-20250115545-A1 TERPENE-CONTAINING LIPIDOIDS FOR GENE DELIVERY UNIV OF SAN DIEGO (US) 2025-04-10 US disclosed
US-20250099383-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACIDS UNIVERSITY OF SAN DIEGO 2025-03-27 US disclosed
EP-4231999-B1 COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACIDS POSEIDA THERAPEUTICS INC (US) 2025-03-05 EP disclosed
US-20240018101-A1 MULTIVALENT TERPENE-BASED BOLAAMPHIPHILES FOR GENE DELIVERY UNIVERSITY OF SAN DIEGO 2024-01-18 US disclosed
US-20240000969-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACIDS UNIVERSITY OF SAN DIEGO 2024-01-04 US disclosed
EP-4232015-A1 MULTIVALENT TERPENE-BASED BOLAAMPHIPHILES FOR GENE DELIVERY University of San Diego (US) 2023-08-30 EP disclosed
EP-4231999-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACIDS Poseida Therapeutics, Inc. (US) 2023-08-30 EP disclosed
WO-2023141279-A2 TERPENE-CONTAINING LIPIDOIDS FOR GENE DELIVERY UNIVERSITY OF SAN DIEGO (US) 2023-07-27 WO disclosed
US-6124354-A TREATMENT OF URINARY INCONTINENCE OR IRRITABLE BOWEL SYNDROME PHARMACIA & UPJOHN AB (SE) 2000-09-26 US disclosed
US-6057332-A Substituted 1,4-dihydropyrimidine-5-carboxylate compounds, their preparation and uses ASTRA AKTIEBOLAG (SE) 2000-05-02 US disclosed
WO-2000008001-A1 SUBSTITUTED ISOXAZOLE AS ESTROGEN RECEPTOR MODULATORS CHIRON CORPORATION (US) 2000-02-17 WO disclosed
US-4506007-A TREATED WITH N,N'-DISUBSTITUTED-S-(DIMETHYLAMINO) ETHYTL)-ISOTHIOUREAS FUJI PHOTO FILM CO., LTD. (JP) 1985-03-19 US disclosed
US-4089891-A HALOGENATED ALIPHATIC HYDROCARBON BIOCHEMIE (OE) 1978-05-16 US disclosed
US-4000188-A ANIONIC SURFACTANTS CIBA-GEIGY CORPORATION (US) 1976-12-28 US disclosed
US-3933877-A Hydrophilic and difficultly volatile biocidal triorganometallic compounds CIBA-GEIGY CORPORATION (US) 1976-01-20 US disclosed
US-3931262-A Hydrophilic and difficultly volatile biocidal triorganotin compounds CIBA-GEIGY CORPORATION (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115545-A1 TERPENE-CONTAINING LIPIDOIDS FOR GENE DELIVERY TTPA, NR1H2, NR1H3 DRD2 4345/4885DRD3 3844/4885TAAR1 4019/4885
US-20240000969-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACIDS LIPC, CD4, HAVCR2 DRD2 4847/4885DRD3 4759/4885TAAR1 3178/4885
US-20240018101-A1 MULTIVALENT TERPENE-BASED BOLAAMPHIPHILES FOR GENE DELIVERY BOLA2; BOLA2B, GHITM, GGPS1 DRD2 3628/4885DRD3 3783/4885TAAR1 1351/4885
US-20110118357-A1 PROCESS FOR PREPARING O-DESMETHYLVENLAFAXINE ADH5, ADH1C, ADH1A DRD2 91/4885DRD3 174/4885TAAR1 852/4885
US-20250099383-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACIDS POLRMT, RNMT, SNRPE DRD2 4665/4885DRD3 4428/4885TAAR1 3636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.