Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307727 | 0.87 | ALDH1A1 (0.41) | MAPTPOLBKDM4EGAAMEN1 | |
| SCHEMBL9307737 | 0.87 | ALDH1A1 (0.41) | MAPTPOLBKDM4EGAAMEN1 | |
| SCHEMBL9309145 | 0.87 | ALDH1A1 (0.41) | MAPTPOLBKDM4EGAAMEN1 | |
| SCHEMBL9309024 | 0.86 | MAPT (0.42) | MAPTTDP1POLBKDM4ERECQL | |
| SCHEMBL14682635 | 0.85 | MEN1 (0.42) | MAPTTDP1POLBKDM4EGAA | |
| SCHEMBL12284558 | 0.84 | ANPEP (0.50) | MAPTPOLBKDM4EMEN1KMT2A | |
| SCHEMBL1121964 | 0.84 | ANPEP (0.50) | MAPTPOLBKDM4EMEN1KMT2A | |
| SCHEMBL7978138 | 0.79 | KMT2A (0.45) | MAPTTDP1KDM4EMEN1KMT2A | |
| SCHEMBL18657109 | 0.78 | MMP2 (0.45) | MAPTPOLBKDM4EMEN1KMT2A | |
| SCHEMBL3345460 | 0.78 | MMP2 (0.45) | MAPTPOLBKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332735-A | Antiamnesic activity | ADIR ET COMPAGNIE (FR) | 1994-07-26 | — | — | US | disclosed |