Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | PPM1B | O75688 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1026556 | 0.86 | TDP1 (0.52) | TDP1KMT2AMAPK1HIF1ACHRNB2 | |
| SCHEMBL13286850 | 0.85 | PPM1B (0.56) | TDP1KMT2AMAPK1HIF1ACHRNB2 | |
| SCHEMBL8191270 | 0.81 | PPM1B (0.52) | TDP1KMT2AMAPK1HIF1ACHRNB2 | |
| SCHEMBL8183690 | 0.81 | PPM1B (0.52) | TDP1KMT2AMAPK1HIF1ACHRNB2 | |
| SCHEMBL8193371 | 0.81 | CES2 (0.53) | TDP1KMT2AMAPK1HIF1ACHRNB2 | |
| SCHEMBL28655049 | 0.80 | TDP1 (0.53) | TDP1KMT2AMAPK1HIF1ACHRNB2 | |
| SCHEMBL21458055 | 0.79 | CHRNB2 (0.51) | TDP1KMT2AMAPK1HIF1ACHRNB2 | |
| SCHEMBL21458031 | 0.79 | CHRNB2 (0.51) | TDP1KMT2AMAPK1HIF1ACHRNB2 | |
| SCHEMBL21458033 | 0.79 | CHRNB2 (0.51) | TDP1KMT2AMAPK1HIF1ACHRNB2 | |
| SCHEMBL9837749 | 0.79 | CES2 (0.52) | TDP1KMT2AMAPK1HIF1ACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374625-A | Bis/hydroxymethyl/cycloalkyl derivatives; viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0468352-A2 | Novel nucleic acid derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-01-29 | — | — | EP | disclosed |