Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.56 |
| ▸ | PYGM | P11217 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.39 |
| ▸ | TK2 | O00142 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025572 | 0.90 | TK1 (0.50) | TK1PYGMBLMCYP1A2GRIA1 | |
| SCHEMBL9025564 | 0.90 | TK1 (0.50) | TK1PYGMBLMCYP1A2GRIA1 | |
| SCHEMBL10827704 | 0.86 | PYGM (0.55) | TK1PYGMBLMCYP1A2GRIA1 | |
| SCHEMBL10827709 | 0.86 | PYGM (0.55) | TK1PYGMBLMCYP1A2GRIA1 | |
| SCHEMBL10827706 | 0.86 | PYGM (0.55) | TK1PYGMBLMCYP1A2GRIA1 | |
| SCHEMBL10828471 | 0.86 | PYGM (0.55) | TK1PYGMBLMCYP1A2GRIA1 | |
| SCHEMBL10828467 | 0.86 | PYGM (0.55) | TK1PYGMBLMCYP1A2GRIA1 | |
| SCHEMBL10827405 | 0.83 | PYGM (0.52) | TK1PYGMP2RY6P2RY14TK2 | |
| SCHEMBL10827403 | 0.83 | PYGM (0.52) | TK1PYGMP2RY6P2RY14TK2 | |
| SCHEMBL10827761 | 0.83 | PYGM (0.52) | TK1PYGMP2RY6P2RY14TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374625-A | Bis/hydroxymethyl/cycloalkyl derivatives; viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0468352-A2 | Novel nucleic acid derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-01-29 | — | — | EP | disclosed |