Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY5 | O95622 | 11/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9310971 | 0.86 | AHCY (0.53) | GSK3ARPS6KA3MAPK14 | |
| SCHEMBL9310964 | 0.86 | AHCY (0.53) | GSK3ARPS6KA3MAPK14 | |
| SCHEMBL10836169 | 0.81 | EGFR (0.56) | ADORA2AGSK3ARPS6KA3MAPK14STING1 | |
| SCHEMBL9789577 | 0.79 | BCHE (0.53) | GSK3ARPS6KA3MAPK14STING1 | |
| SCHEMBL9707227 | 0.78 | CHKA (0.36) | ADCY5ADORA2A | |
| SCHEMBL9309410 | 0.78 | CHKA (0.36) | ADCY5ADORA2A | |
| SCHEMBL9444432 | 0.78 | ABCB1 (0.56) | GSK3ARPS6KA3MAPK14STING1 | |
| SCHEMBL9311362 | 0.78 | AHCY (0.42) | GSK3ARPS6KA3MAPK14STING1 | |
| SCHEMBL9311355 | 0.78 | AHCY (0.42) | GSK3ARPS6KA3MAPK14STING1 | |
| SCHEMBL338780 | 0.77 | POLB (0.60) | GSK3ARPS6KA3MAPK14STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374625-A | Bis/hydroxymethyl/cycloalkyl derivatives; viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0468352-A2 | Novel nucleic acid derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-01-29 | — | — | EP | disclosed |