Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | GSK3A | P49840 | 2/20 | 0.56 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | AHCY | P23526 | 1/20 | 0.54 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.54 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.53 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28565449 | 0.88 | ABCB1 (0.54) | ABCB1GSK3ARPS6KA3MAPK14BCHE | |
| SCHEMBL11451041 | 0.85 | BCHE (0.57) | BCHEAHCY | |
| SCHEMBL11654898 | 0.85 | BCHE (0.57) | BCHEAHCY | |
| SCHEMBL9079102 | 0.85 | AHCY (0.55) | BCHEAHCY | |
| SCHEMBL338780 | 0.84 | POLB (0.60) | ABCB1GSK3ARPS6KA3MAPK14STING1 | |
| SCHEMBL11644877 | 0.84 | ABCB1 (0.77) | ABCB1GSK3ARPS6KA3MAPK14LMNA | |
| SCHEMBL9789577 | 0.84 | BCHE (0.53) | ABCB1GSK3ARPS6KA3MAPK14BCHE | |
| SCHEMBL441535 | 0.84 | ABCB1 (0.77) | ABCB1GSK3ARPS6KA3MAPK14LMNA | |
| SCHEMBL9310971 | 0.83 | AHCY (0.53) | ABCB1GSK3ARPS6KA3MAPK14AHCY | |
| SCHEMBL9310964 | 0.83 | AHCY (0.53) | ABCB1GSK3ARPS6KA3MAPK14AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483345-A4 | PROMOTER LIGATION ACTIVATED TRANSCRIPTION AMPLIFICATION OF NUCLEIC ACID SEQUENCES | — | 1993-05-26 | — | — | EP | disclosed |
| EP-0483345-A1 | PROMOTER LIGATION ACTIVATED TRANSCRIPTION AMPLIFICATION OF NUCLEIC ACID SEQUENCES | LIFE TECHNOLOGIES INC. (US) | 1992-05-06 | — | — | EP | disclosed |
| WO-1991018115-A1 | PROMOTER LIGATION ACTIVATED TRANSCRIPTION AMPLIFICATION OF NUCLEIC ACID SEQUENCES | LIFE TECHNOLOGIES, INC. (US) | 1991-11-28 | — | — | WO | disclosed |