Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 8/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | GSK3A | P49840 | 2/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | HNMT | P50135 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9310964 | 1.00 | AHCY (0.53) | AHCYADORA2BGSK3ARPS6KA3MAPK14 | |
| SCHEMBL9310515 | 0.86 | ADCY5 (0.57) | GSK3ARPS6KA3MAPK14 | |
| SCHEMBL9311362 | 0.84 | AHCY (0.42) | AHCYADORA2BGSK3ARPS6KA3MAPK14 | |
| SCHEMBL9311355 | 0.84 | AHCY (0.42) | AHCYADORA2BGSK3ARPS6KA3MAPK14 | |
| SCHEMBL9444432 | 0.83 | ABCB1 (0.56) | AHCYGSK3ARPS6KA3MAPK14ABCB1 | |
| SCHEMBL10836169 | 0.83 | EGFR (0.56) | GSK3ARPS6KA3MAPK14ABCB1 | |
| SCHEMBL338780 | 0.83 | POLB (0.60) | GSK3ARPS6KA3MAPK14ABCB1 | |
| SCHEMBL441535 | 0.78 | ABCB1 (0.77) | ADORA2BGSK3ARPS6KA3MAPK14ABCB1 | |
| SCHEMBL9789577 | 0.78 | BCHE (0.53) | AHCYGSK3ARPS6KA3MAPK14ABCB1 | |
| SCHEMBL11644877 | 0.78 | ABCB1 (0.77) | ADORA2BGSK3ARPS6KA3MAPK14ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374625-A | Bis/hydroxymethyl/cycloalkyl derivatives; viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0468352-A2 | Novel nucleic acid derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-01-29 | — | — | EP | disclosed |